Born in Grosseto, Italy. Studied illustration at the IED, Europe Institute of Design after which she published works in over 30 books. In 1993 she shifted her focus to painting. In 1998 she moved permanently to New York where she started her research as an artist painter full time. In 2006 she was selected by the American Association of University Women in the “Emerging Women Artists Juried Exhibition” New York Design Center .  Her work has being collected and commissioned by both public and private clients; Soros collection, Serafina group, CityCinema group, Jerry Saltz collection. Martello  collaborates with: galleria Giovanni Bonelli, Italy, Pen&Brush gallery NYC, Parlor gallery, NJ.


In 2014 she won the selection for juried exhibition  "Understanding Media, the Extension of Human Being” organized by CallforBushwick, during BOS, in Brooklyn, NYC,  she exhibited at Tibet House Museum US, and she took part of ''Transcending Tibet'' NYC curated by Davide Quadrio.


In 2015 she has being commissioned a trittico for the permanent collection of Metropoliz MAAM Museum of Rome by curators Giorgio de Finis, she's being selected by curator Rick Kinsel, director of Vilcek foundation to be part of ''Domesticity Revisited'' at Pen&Brush NYC, and exhibited at AQUA Miami Art Fair, and in 2016 at Context NYC.  In 2016/2017 she’s selected to be part of Woodenwallsproject a public art program with 3 Murals installation in Asbury Park, NJ, same year she exhibited at A.I.R. gallery '' Overlap; Life tapestries'' curated by Vida Sabbaghi, an itinerant group show that travel to PennState gallery in 2018.


In the same year, Pen&Brush hosted  a large scale solo show of 8 years of Martello's paintings, ‘’Future is Goddess’’  and she’s  a featured artist in the Public Art Project LaMer-WaveWalk NYC with WeAreProjectZero, alongside notable artists and influencers.


In 2018 she is part of SuperSHE a group show at Galleria Giovanni Bonelli, Milan, and Beauty in the Beast a group show curated by COPE-NYC at Soulangh Cultural park in Taiwan, where she also does an Art Residency painting a mural for the National Museum of Children. Ending 2018 with 2 person show Michela Martello / Tricia Wright at Pen&Brush NYC. In 2019 she has a solo show in Raleigh, NC, ArtSpace, ''Consequential Stranger'' and a 2 person show '' Everything Has A Vortex " with artist Shigeru Oyatani in Tainan city - Taiwan, curated by COPE-NYC, she's also part of the third iteration ''Overlap; LIfe Tapestries'' at Pen&Brush NYC, her piece Time Zone is selected to be exhibited in the group show MAAM at MACRO, Museum of Modern Art, Rome. In 2020, Martello is invited by the curatorial program of Tainan Art Museum to be part of the group show ''Art Point'', and a first female solo exhibit at galleria Giovanni Bonelli in Milan,''Of The Earth'' in the same year she's selected by Jarry Saltz for the prestigious publication New American painting. In 2022, she's curating the group show The Fire and the Cow at galleria Giovanni Bonelli, and she is selected by Wendy Olsoff and Eden Reeding by PPOW for the Artsy auction to benefit Pen+Brush.